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Cytokines in Human Health: Immunotoxicology, Pathology, and Therapeutic Applications (Methods in Pharmacology and Toxicology)
Cytokines in Human Health: Immunotoxicology, Pathology, and Therapeutic Applications (Methods in Pharmacology and Toxicology)
Over the past three decades the field of immunotoxicology, the study of the effects of exposure to drugs, chemicals, or physical/environmental agents on the structure and function of the immune system has benefited from an increasingly detailed understanding of the cellular and molecular basis of innate and acquired immunity....
The Physiological Bases of Cognitive and Behavioral Disorders
The Physiological Bases of Cognitive and Behavioral Disorders

Up to twenty percent of the American population suffers from a diagnosable mental disorder, and cross-national studies suggest a high prevalence of such disorders elsewhere. In recent decades, advances in our knowledge of the brain are causing us to question many of the theories underlying traditional approaches to diagnosing and treating...

Rudolph's Pediatrics
Rudolph's Pediatrics
The 21st edition of Rudolph's Pediatrics continues a tradition of evolving and adapting to changes in pediatric medicine. Originally published in 1897 as Diseases of Infancy and Childhood,...
Visual Prosthesis and Ophthalmic Devices: New Hope in Sight (Ophthalmology Research)
Visual Prosthesis and Ophthalmic Devices: New Hope in Sight (Ophthalmology Research)
The history of medicine has been substantially defined by a small number of monumental discoveries. Most of these breakthroughs have emerged from the biological sciences. One of the first great breakthroughs was the recognition by Koch in 1884 that pathogens could be transmitted from one living organism to another to cause disease....
Comprehensive Textbook of Genitourinary Oncology
Comprehensive Textbook of Genitourinary Oncology

Thoroughly revised for its Third Edition, this volume is the most comprehensive, multidisciplinary text on genitourinary cancers. This edition has two new editors—Frans M.J. Debruyne and W. Marston Linehan—and more than 50% new contributors. Seventeen new chapters cover familial prostate cancer, biology of bone...

Streptomyces in Nature and Medicine: The Antibiotic Makers
Streptomyces in Nature and Medicine: The Antibiotic Makers

This is an insiders account of 50 years of genetic studies of the soil-inhabiting microbes that produce most of the antibiotics used to treat infections, as well as anti-cancer, anti-parasitic and immunosuppressant drugs. The book begins by describing how these microbes the actinomycetes were discovered in the latter part of the nineteenth...

Handbook of Transcription Factor NF-kappaB
Handbook of Transcription Factor NF-kappaB

Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB...

BioMEMS and Biomedical Nanotechnology
BioMEMS and Biomedical Nanotechnology
Numerous miniaturized DNA microarray, DNA chip, Lab on a Chip and biosensor devices have been developed and commercialized. Such devices are improving theway many important genomic and proteomic analyses are performed in both research and clinical diagnostic laboratories. The development of these technologies was enabled by a...
Infections and the Cardiovascular System: New Perspectives (Emerging Infectious Diseases of the 21st Century)
Infections and the Cardiovascular System: New Perspectives (Emerging Infectious Diseases of the 21st Century)
Infectious agents have been recognized to involve the heart and vascular system for well over a century. Traditional concepts and teachings of their involvement in the pathogenesis of disease have been by a few established mechanisms. Bacterial and occasionally fungal microorganisms were known to invade and multiply on the...
Computational Cardiology: Modeling of Anatomy, Electrophysiology, and Mechanics (Lecture Notes in Computer Science)
Computational Cardiology: Modeling of Anatomy, Electrophysiology, and Mechanics (Lecture Notes in Computer Science)
Biomedical research is at a critical point at present. The research has led to an enormous amount of data and models describing these data, but approaches for application, formalization and integration of this knowledge from the molecular to the system level are still topics of ongoing research and certainly far from fully...
Nutrient-Gene Interactions in Cancer
Nutrient-Gene Interactions in Cancer

The complete mapping of the human genome, along with the development of sophisticated molecular technologies, has accelerated research on the relationship between nutrients and genes. This has led to compelling evidence garnered from epidemiological and experimental observations supporting the idea that the interaction between nutrients and...

Microarrays in Clinical Diagnostics (Methods in Molecular Medicine)
Microarrays in Clinical Diagnostics (Methods in Molecular Medicine)
Within the last decade, microarray technology has evolved from an emerging technology developed and used by a few laboratories into a well-established technology used in laboratories all over the world. In fact, the need to characterize genetic alterations is one of the highest priorities for the future of medicine and the...
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